Proviron (mesterolone) is an orally administered anabolic-androgenic steroid (AAS) primarily used to treat androgen deficiency in men. Known for its mild androgenic properties and lack of significant anabolic effects, Proviron is often used to address low testosterone levels, improve fertility, and enhance overall male vitality. Its unique profile makes it a versatile option in androgen therapy.

Medical Uses

Proviron is prescribed to treat conditions related to androgen deficiency, such as hypogonadism, infertility, and delayed puberty in males. It is also used to counteract symptoms like reduced libido, fatigue, and mood disturbances caused by low testosterone levels. Additionally, Proviron has applications in improving sperm quality in men experiencing infertility related to hormonal imbalances.

Mechanism of Action

Proviron works by binding to androgen receptors, mimicking the effects of natural testosterone in the body. Unlike other AAS, it has a low anabolic-to-androgenic ratio, which means its effects are predominantly androgenic, such as promoting male characteristics and libido enhancement. Proviron also inhibits the conversion of testosterone to estrogen by acting as an aromatase inhibitor, which helps maintain optimal hormonal balance.

Side Effects

While generally well-tolerated, Proviron can cause side effects, especially with prolonged or high-dose use. Common side effects include oily skin, acne, and hair loss in individuals predisposed to male pattern baldness. In rare cases, it may lead to mood changes or prostate-related issues. Patients with pre-existing liver conditions or a history of prostate cancer should avoid Proviron due to potential risks.

Interactions

Proviron may interact with other medications, particularly anticoagulants and other hormonal treatments. Such interactions can alter the effectiveness of the medications or increase the likelihood of side effects. Patients should inform their healthcare provider about any other medications or supplements they are taking before starting Proviron therapy.