Stanozolol is an anabolic steroid derived from dihydrotestosterone (DHT), known by its brand name Winstrol. It has both oral and injectable forms and is primarily used in medical and non-medical settings for its anabolic properties.

Medical Uses

Stanozolol has several approved medical uses:

1. Angioedema: It is used to reduce the frequency and severity of attacks of angioedema, a condition characterized by episodes of swelling in the face, extremities, and throat.
2. Burns: Stanozolol has been used to promote recovery in patients with severe burns by increasing collagen synthesis, which helps in tissue repair.

Mechanism of Action

Stanozolol exerts its effects through several mechanisms:

• Androgen Receptor Binding: It binds to androgen receptors in various tissues, promoting anabolic effects such as muscle growth and increased strength.
• Protein Synthesis: Stanozolol enhances protein synthesis, leading to significant gains in muscle mass.
• Collagen Synthesis: It stimulates collagen synthesis in connective tissues, aiding in tissue repair and recovery.

Side Effects

While effective, stanozolol can have several potential side effects:

1. Androgenic Effects: May cause increased body hair growth, acne, and in women, virilization (masculinization) symptoms like deepening of the voice and enlargement of the clitoris.
2. Cardiovascular Issues: Stanozolol can negatively impact cholesterol levels, leading to an increase in LDL (bad cholesterol) and a decrease in HDL (good cholesterol).
3. Liver Toxicity: Stanozolol is hepatotoxic and can cause liver damage, particularly when used for extended periods or at high doses.
4. Joint Pain: Some users report joint pain or discomfort while using stanozolol.

Interactions

Stanozolol may interact with medications affecting liver function or those that alter hormonal balance. Specific interactions may include:

• Aromatase Inhibitors: These drugs can alter the metabolism of stanozolol.
• Selective Estrogen Receptor Modulators (SERMs): They can interact with stanozolol, impacting its effectiveness and the body’s hormonal balance.
• 5-Alpha Reductase Inhibitors: These medications can influence the androgenic activity of stanozolol.
• Anti-Androgens: These drugs can counteract some of the effects of stanozolol.